Sufficient antipsychotic coverage with oral risperidone or the previous antipsychotic should be ensured during the three-week lag period following the first Risperidone depot ( consta) injection.
Sufficient antipsychotic coverage should be ensured during the three-week lag period following the first Consta injection
After a single intramuscular injection with Risperidone depot, the release profile consists of a small initial release of risperidone (<1% of the dose), followed by a lag time of 3 weeks. The main release of risperidone starts from Week 3 onwards, is maintained from 4 to 6 weeks, and subsides by Week 7. Oral antipsychotic supplementation should therefore be given during the first 3 weeks of Riperidone depot treatment