How long do you continue with oral risperidone after starting depot risperidone??

14.09.2012

Sufficient antipsychotic coverage with oral risperidone or the previous antipsychotic should be ensured during the three-week lag period following the first Risperidone depot ( consta)  injection.

Sufficient antipsychotic coverage should be ensured during the three-week lag period following the first Consta injection

After a single intramuscular injection with Risperidone depot, the release profile consists of a small initial release of risperidone (<1% of the dose), followed by a lag time of 3 weeks. The main release of risperidone starts from Week 3 onwards, is maintained from 4 to 6 weeks, and subsides by Week 7. Oral antipsychotic supplementation should therefore be given during the first 3 weeks of Riperidone depot treatment

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